Table 4Clinical evidence summary: ED closure versus 24 hour ED access

OutcomesNo of Participants (studies) Follow upQuality of the evidence (GRADE)Relative effect (95% CI)Anticipated absolute effects
Risk with ControlRisk difference with ED closure versus 24 hour ED access (95% CI)
Male ED visit rate

14485

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of male ED visits in the control group was

130 per 1000

The mean controlled change in the intervention group was

10 fewer per 1000

(40 fewer to 20 more)

Female ED visit rate

14244

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of female ED visits in the control group was

80 per 1000

The mean controlled change in the intervention group was

10 more per 1000

(10 fewer to 30 more)

Male admission rate

14485

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of male admissions in the control group was

170 per 1000

The mean controlled change in the intervention group was

20 fewer per 1000

(60 fewer to 20 more)

Female admission rate

14244

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of female admissions in the control group was

190 per 1000

The mean controlled change in the intervention group was

40 more per 1000

(40 fewer to 120 more)

Male in-person GP consultation rate

14485

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of male in-person GP consultations in the control group was

2840 per 1000

The mean controlled change in the intervention group was

30 more per 1000

(420 fewer to 480 more)

Female in-person GP consultation rate

14244

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of female in-person GP consultations in the control group was

3850 per 1000

The mean controlled change in the intervention group was

260 fewer per 1000

(610 fewer to 90 more)

Male telephone GP consultation rate

14485

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of male telephone GP consultations in the control group was

1970 per 1000

The mean controlled change in the intervention group was

310 more per 1000

(90 fewer to 710 more)

Female telephone GP consultation rate

14244

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of female telephone GP consultations in the control group was

3300 per 1000

The mean controlled change in the intervention group was

350 fewer per 1000

(820 fewer to 120 more)

Male home GP consultation rate

14485

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of male home GP consultations in the control group was

150 per 1000

The mean controlled change in the intervention group was

40 more per 1000

(50 fewer to 130 more)

Female home GP consultation rate

14244

(1 study)

1-2 years

⊕⊝⊝⊝

VERY LOWa

due to risk of bias

-

The mean final rate of female home GP consultations in the control group was

240 per 1000

The mean controlled change in the intervention group was

120 fewer per 1000

(230 to 10 fewer)

Note: due to rounding data only accurate to the nearest 10 per 1000.

(a)

All non-randomised studies automatically downgraded due to selection bias. Studies may be further downgraded by 1 increment if other factors suggest additional high risk of bias, or 2 increments if other factors suggest additional very high risk of bias.

From: Chapter 16, Emergency department opening hours

Cover of Emergency and acute medical care in over 16s: service delivery and organisation
Emergency and acute medical care in over 16s: service delivery and organisation.
NICE Guideline, No. 94.
National Guideline Centre (UK).
Copyright © NICE 2018.

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