Contents

• Clinical guidelines update
• 1. Summary section
  • 1.1. Update information
  • 1.2. Strength of recommendations
  • 1.3. Information for consultation
  • 1.4. Recommendations
  • 1.5. Patient-centred care
  • 1.6. Methods
  • 1.7. Introduction
  • 1.8. Review question
  • 1.9. Clinical evidence review
  • 1.10. Health economics
  • 1.11. Evidence statements
  • 1.12. Evidence to recommendations
  • 1.13. Recommendations
  • 1.14. Research recommendations
• 2. References
• 3. Glossary and abbreviations
• Appendices
  • Appendix A. Committee members and NICE teams
  • Appendix B. Declarations of interest
  • Appendix C. Review protocol
  • Appendix D. Search strategy
  • Appendix E. Review flowchart
  • Appendix F. Excluded studies
  • Appendix G. Evidence tables
  • Appendix H. GRADE profiles
  • Appendix I. Forest plots
  • Appendix J. Economic search strategy
  • Appendix K. Economic review flowchart

Final

September 2016: A data extraction error in the analysis of phosphodiesterase 5 inhibitors versus placebo for the outcome of symptom score (IPSS) was corrected. The information for Kim 2011 has been changed to −1.6 (SE 0.8485). This error did not affect the recommendations.

Developed by the National Institute for Health and Care Excellence

Disclaimer: Healthcare professionals are expected to take NICE clinical guidelines fully into account when exercising their clinical judgement. However, the guidance does not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of each patient, in consultation with the patient and/or their guardian or carer.