Table 71Summary of Evidence Available for All-Cause Death Among Patients With a Drug-Eluting Stent: Network Meta-Analysis, 12 Months Versus > 12 Months

Systematic ReviewIncluded RCTsStent TypeNo. of PatientsType of AnalysisComparison; Direction of EstimateEffect Estimate (95% CrI)
Xie 2016
  • PRODIGYa
  • DES-LATE
  • ARCTIC-Interruption
  • DAPTa
DES17,743bOR, RE12 mo vs. 24 mo; OR < 1 indicates lower odds in extended groupOR 0.78 (0.31 to 2.63)c
12 mo vs. 30 mo; OR > 1 indicates higher odds in extended groupOR 1.20 (0.56 to 3.03)d
12 mo vs. 36 mo; OR > 1 indicates higher odds in extended groupOR 1.30 (0.60 to 3.57)e

CrI = credible interval; DAPT = dual antiplatelet therapy; DES = drug-eluting stent; mo = months; OR = odds ratio; RCT = randomized controlled trial; RE = random effects; vs. = versus.

a

Patients with a bare-metal stent were excluded from analysis.

b

The full network including all DAPT durations included 17,743 patients. It is unclear how many patients contributed data to each comparison.

c

Data reversed for presentation: Original data reported such that OR > 1 indicates higher odds in short group (OR 1.28; 95% CrI, 0.38 to 3.21).

d

Data reversed for presentation: Original data reported such that OR < 1 indicates lower odds in short group (OR 0.83; 95% CrI, 0.33 to 1.77).

e

Data reversed for presentation: Original data reported such that OR < 1 indicates lower odds in short group (OR 0.77; 95% CrI, 0.28 to 1.67).

From: Results

Cover of Dual Antiplatelet Therapy Following Percutaneous Coronary Intervention: A Review of the Clinical Impact of Treatment Duration
Dual Antiplatelet Therapy Following Percutaneous Coronary Intervention: A Review of the Clinical Impact of Treatment Duration [Internet].
CADTH Technology Review, No. 8.
Wells GA, Elliott J, Kelly S, et al.
Copyright © 2017 Canadian Agency for Drugs and Technologies in Health.

The copyright and other intellectual property rights in this document are owned by CADTH and its licensors. These rights are protected by the Canadian Copyright Act and other national and international laws and agreements. Users are permitted to make copies of this document for non-commercial purposes only, provided it is not modified when reproduced and appropriate credit is given to CADTH and its licensors.

Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International licence (CC BY-NC-ND), a copy of which is available at http://creativecommons.org/licenses/by-nc-nd/4.0/

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.