From: Gene Frequently Asked Questions
Gene Help [Internet].
Bethesda (MD): National Center for Biotechnology Information (US); 2005-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Figure 1.
The Genomic Context section for hemE of Rhizobium leguminosarum bv. viciae 3841 (GeneID 4402322), a gene that spans the origin of replication of a circular genome. The complete genomic RefSeq accession is shown as a linearized molecule opened at the origin. The spanning gene is colored in maroon. Note that the relationship between neighboring genes is affected by this rendering when compared to the circular genome.