Trichloroethylene, Tetrachloroethylene, and Some Other Chlorinated Agents
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, No. 106
Authors
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans.This Volume of the IARC Monographs provides an assessment of the carcinogenic hazards associated with exposure to seven chlorinated solvents, including trichloroethylene, tetrachloroethylene, and their metabolites (dichloroacetic acid, trichloroacetic acid, and chloral hydrate). All these agents were previously assessed by IARC Working Groups more than 10 years ago, and new epidemiological and mechanistic evidence has been considered in this reevaluation.
Trichloroethylene has been used in several industries, such as manufacture and repair of aircraft and automobiles, and in screw-cutting, while tetrachloroethylene is widely used in dry-cleaning and as a feedstock for the production of chlorinated chemicals.
The IARC Monographs Working Group relied on epidemiological evidence, carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.
Corrigenda to the IARC Monographs are published online at http://monographs.iarc.fr/ENG/Publications/corrigenda.php.
Corrigenda to Volume 106. (PDF, 92K)
This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, which met in Lyon, 2-9 October 2012
Lyon, France - 2014
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IARC Library Cataloguing in Publication Data
- Trichloroethylene, Tetrachloroethylene and Some Other Chlorinated Agents / IARC Working Group on the Evaluation of Carcinogenic Risks to Humans (2012: Lyon, France)
- (IARC monographs on the evaluation of carcinogenic risks to humans ; v. 106)
- 1. Carcinogens 2. Humans 3. Neoplasms – chemically induced 4. Occupational exposure 5. Trichloroethylene – adverse effects 6. Tetrachloroethylene – adverse effects 7. Dichloroacetic Acid adverse effects 8. Trichloroacetic Acid – adverse effects 9. Chloral Hydrate adverse effects
- I. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
- II. Series
- ISBN 978 92 832 01724 (NLM Classification: W1)
- ISSN 1017-1606
- Cover design: Au-delà des mots
- Cover image : ©Cindy Roudier, la République du Centre