Figure 7. . Mechanism of the effect of carbenoxolone.

Figure 7.

Mechanism of the effect of carbenoxolone. Carbenololone inhibits of conversion of cortisol to cortisone in the kidney, resulting in the enhancement of the effect of cortisol as a ligand for MR. Dexamethasone suppressed cortisol production and reversing the beneficial effect of carbenoxolone in our patient with PHA1.

From: Aldosterone Deficiency and Resistance

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