BSN38-MSSA1 - BioSample - NCBI

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BSN38-MSSA1

Identifiers: BioSample: SAMN39933410; Sample name: Staphylococcus aureus str BSN38-MSSA1

Organism: Staphylococcus aureus
cellular organisms; Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus

Package: Pathogen: clinical or host-associated; version 1.0

Attributes

strain	BSN38-MSSA1
collected by	Andrew D. Berti
collection date	2020-09-07
geographic location	USA: Detroit, MI
host	Homo sapiens
host disease	osteomyelitis
isolation source	blood
latitude and longitude	42.33 N 83.05 W
genotype	ST97-MSSA CC97
host age	41
host description	Patient with history of staphylococcal osteomyelitis and active substance use disorder presents with acute neck pain at his heroin injection site. Patient was observed to be bacteremic and treated medically with vancomycin plus cefazolin. Clinical course was complicated by extensive spinal osteomyelitis and paraspinal abscesses, multiple pulmonary opacities consistent with septic emboli and tricuspid valve endocarditis. Blood cultures consistently grew out two populations of Staphylococcus aureus, one methicillin-resistant and one methicillin-susceptible. Therapy was modified to daptomycin plus cefazolin resulting in pure methicillin-resistant cultures then clear blood cultures. The patient experienced relapse bacteremia two weeks later with daptomycin nonsusceptible methicillin-resistant Staphylococcus aureus and therapy was modified again to ceftaroline plus daptomycin. The following week the patient left against medical advice and was prescribed oral linezolid to complete therapy. Duration of initial bacteremia: 14 days.
host disease outcome	chronic disease
host sex	male
host subject id	BSS38

Description: alias: B0575. Other isolates from this patient: BSN38-MRSA1, BSN38-MRSA2, BSN38-MRSA3, BSN38-MRSA4, BSN38-MSSA2

BioProject: PRJNA1048360 Staphylococcus aureus
Retrieve all samples from this project

Submission: Wayne State University, Andrew Berti; 2024-02-13

Antibiogram
Antibiotic	Resistance phenotype	Measurement sign	Measurement	Measurement units	Laboratory typing method	Laboratory typing platform	Vendor	Laboratory typing method version or reagent	Testing standard
clindamycin	susceptible	<=	0.5	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
erythromycin	susceptible	<=	0.5	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
gentamicin	susceptible	<=	1	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
oxacillin	susceptible	==	0.5	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
penicillin	resistant	>	1	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
rifampin	susceptible	<=	0.5	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
trimethoprim-sulfamethoxazole	susceptible	<=	0.5/9.5	mg/L	MIC	Phoenix	Becton Dickinson		CLSI
vancomycin	susceptible	==	1	mg/L	MIC	Phoenix	Becton Dickinson		CLSI

Accession:: SAMN39933410
ID:: 39933410

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