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CGFF2

Identifiers
BioSample: SAMEA91282918; SRA: ERS1559825
Organism
Nakaseomyces glabratus
cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces
Attributes
descriptionIn this work a phenotypic screening over a cohort of clinical Candida glabrata isolates was undertaken leading to the identification of an isolate, named FFUL887, which was recovered from the urinary tract and that was found to be resistant to both fluconazole and voriconazole. To better understand the molecular mechanisms underlying the azole-resistance phenotype of the FFUL887 strain its genome sequence was obtained, annotated and compared with the one of the reference strain CBS138, susceptible to the two above mentioned azoles and having an intestinal origin. Besides providing clues to mechanisms underlying acquisition of azole resistance inside the host, our results also provide insights into the different responses evolved by C. glabrata in the colonization of different niches.
sample nameERS1559825
isolateFFUL887
AliasCGFF2
ENA checklistERC000011
INSDC center nameTechnische Universitat Munchen - WZW
INSDC first public2017-10-23T17:03:30Z
INSDC last update2017-02-15T12:23:42Z
INSDC statuspublic
SRA accessionERS1559825
TitleSequencing and comparative genomics of Candida glabrata isolate FFUL887
BioProject
PRJEB15305 Candida glabrata FFUL887
Retrieve all samples from this project

Submission
EBI; 2017-10-24
Accession:
SAMEA91282918
ID:
7829277

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