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Genome Information for Mus musculus
Effects of YBX1 activation in PPARγ-indcuded C3H/10T1/2-SAM pre-adipocytes on the transcriptome of cells during early differentation stages
Overall design: C3H/10T1/2-SAM pre-adipocytes containing dCas9-VP64 and MS2-P65-HSF1 were transfected with guide RNA taregting PPARγ or a combination of guides taregting PPARγ and YBX1 two days before differentiation start to model gain of funtion in pre-adipocytes. Transcriptome was analysed for day 0, day 2 and day 4 of differentiation.
Accession | PRJNA627345; GEO: GSE149083 |
Data Type | Transcriptome or Gene expression |
Scope | Multiisolate |
Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
Publications | Rabiee A et al., "White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment.", Mol Metab, 2021 Feb;44:101137 |
Submission | Registration date: 22-Apr-2020 Integrative Physiology, NNF Center for Basic Metabolic Research, Copenhagen University |
Relevance | Model Organism |
Project Data:
Resource Name | Number of Links |
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Sequence data |
SRA Experiments | 51 |
Publications |
PubMed | 1 |
PMC | 1 |
Other datasets |
BioSample | 51 |
GEO DataSets | 1 |