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Accession: PRJNA666420 ID: 666420

The Atypical Antipsychotic Risperidone Targets Central Melanocortin 4 Receptors to Cause Weight (house mouse)

See Genome Information for Mus musculus
hypothalami from female C57BL/6 mice fed either the risperidone or the control diet for 28 days, along with those from a third group of “pair-fed” mice that were given the risperidone diet, but limited to the same amount that Ctrl_ Ad lib mice had consumed. Overall design: Ctrl_Ad.lib, n=7; RIS_Ad lib, n=7; RIS_PF, n=6
AccessionPRJNA666420; GEO: GSE158751
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLi L et al., "The atypical antipsychotic risperidone targets hypothalamic melanocortin 4 receptors to cause weight gain.", J Exp Med, 2021 Jul 5;218(7)
SubmissionRegistration date: 29-Sep-2020
UT Southwestern Medical Center
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments20
Publications
PubMed1
PMC1
Other datasets
BioSample20
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Gbases146
Data volume, Mbytes97590

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