Publications (total 3922) Less... | - Liu H et al., "Three-dimensional genome structure and function.", MedComm (2020), 2023 Aug;4(4):e326
More...- Liu H et al., "Three-dimensional genome structure and function.", MedComm (2020), 2023 Aug;4(4):e326
- Yuan H et al., "MNS16A polymorphism of the TERT gene on cancer risk: a systematic review and meta-analysis.", Nucleosides Nucleotides Nucleic Acids, 2023;42(12):1004-1018
- Ming Z et al., "SOX9 in organogenesis: shared and unique transcriptional functions.", Cell Mol Life Sci, 2022 Sep 17;79(10):522
- Watts JA et al., "A common transcriptional mechanism involving R-loop and RNA abasic site regulates an enhancer RNA of APOE.", Nucleic Acids Res, 2022 Nov 28;50(21):12497-12514
- Zhou J "Sequence-based modeling of three-dimensional genome architecture from kilobase to chromosome scale.", Nat Genet, 2022 May;54(5):725-734
- Neumayr C et al., "Differential cofactor dependencies define distinct types of human enhancers.", Nature, 2022 Jun;606(7913):406-413
- Kousathanas A et al., "Whole-genome sequencing reveals host factors underlying critical COVID-19.", Nature, 2022 Jul;607(7917):97-103
- Jagoda E et al., "Detection of Neanderthal Adaptively Introgressed Genetic Variants That Modulate Reporter Gene Expression in Human Immune Cells.", Mol Biol Evol, 2022 Jan 7;39(1)
- Terao M et al., "Turnover of mammal sex chromosomes in the Sry-deficient Amami spiny rat is due to male-specific upregulation of Sox9.", Proc Natl Acad Sci U S A, 2022 Dec 6;119(49):e2211574119
- Long E et al., "Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity.", Am J Hum Genet, 2022 Dec 1;109(12):2210-2229
- Nekolova J et al., "Modern diagnostic and therapeutic approaches in familial maculopathy with reference to North Carolina macular dystrophy.", Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, 2022 Dec;166(4):418-427
- Simtong P et al., "RHD 1227 A and hybrid Rhesus box analysis in Thai RhD+ and RhD- blood donors: Prevalence, RHD zygosity, and molecular screening.", Transfus Apher Sci, 2022 Dec;61(6):103496
- Hansen TJ et al., "ATAC-STARR-seq reveals transcription factor-bound activators and silencers within chromatin-accessible regions of the human genome.", Genome Res, 2022 Aug 25;32(8):1529-1541
- COVID-19 Host Genetics Initiative "A first update on mapping the human genetic architecture of COVID-19.", Nature, 2022 Aug;608(7921):E1-E10
- Thibord F et al., "A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors.", HGG Adv, 2022 Apr 14;3(2):100095
- Horowitz JE et al., "Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease.", Nat Genet, 2022 Apr;54(4):382-392
- Guo H et al., "Identifying shared genetic loci between coronavirus disease 2019 and cardiovascular diseases based on cross-trait meta-analysis.", Front Microbiol, 2022;13:993933
- Qian Z et al., "Whole genome sequencing identifies a cryptic SOX9 regulatory element duplication underlying a case of 46,XX ovotesticular difference of sexual development.", Am J Med Genet A, 2021 Sep;185(9):2782-2788
- Sadeghi-Bojd Y et al., "RHD Genotyping of Rh-Negative and Weak D Phenotype among Blood Donors in Southeast Iran.", Int J Hematol Oncol Stem Cell Res, 2021 Oct 1;15(4):213-220
- Shang D et al., "Sex differences in autophagy-mediated diseases: toward precision medicine.", Autophagy, 2021 May;17(5):1065-1076
- Nasser J et al., "Genome-wide enhancer maps link risk variants to disease genes.", Nature, 2021 May;593(7858):238-243
- Vining B et al., "Diverse Regulation but Conserved Function: SOX9 in Vertebrate Sex Determination.", Genes (Basel), 2021 Mar 26;12(4)
- Matteocci A et al., "Two new RHD alleles with deletions spanning multiple exons.", Transfusion, 2021 Mar;61(3):682-686
- Shelton JF et al., "Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity.", Nat Genet, 2021 Jun;53(6):801-808
- Kitahama K et al., "Reduced H3K27me3 levels in diffuse gliomas: association with 1p/19q codeletion and difference from H3K27me3 loss in malignant peripheral nerve sheath tumors.", Brain Tumor Pathol, 2021 Jan;38(1):23-29
- Nambirajan A et al., "EZH2 inhibitory protein (EZHIP/Cxorf67) expression correlates strongly with H3K27me3 loss in posterior fossa ependymomas and is mutually exclusive with H3K27M mutations.", Brain Tumor Pathol, 2021 Jan;38(1):30-40
- Matsuzaki H et al., "Orientation of mouse H19 ICR affects imprinted H19 gene expression through promoter methylation-dependent and -independent mechanisms.", Commun Biol, 2021 Dec 17;4(1):1410
- Watzky M et al., "Assessing the consequences of environmental exposures on the expression of the human receptor and proteases involved in SARS-CoV-2 cell-entry.", Environ Res, 2021 Apr;195:110317
- Ridnik M et al., "Cis-Regulatory Control of Mammalian Sex Determination.", Sex Dev, 2021;15(5-6):317-334
- Sacconi A et al., "TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients.", J Exp Clin Cancer Res, 2020 Sep 23;39(1):200
- Zhou L et al., "Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells.", bioRxiv, 2020 Sep 2;
- Peng T et al., "STARR-seq identifies active, chromatin-masked, and dormant enhancers in pluripotent mouse embryonic stem cells.", Genome Biol, 2020 Sep 10;21(1):243
- Aguiar JA et al., "Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue.", Eur Respir J, 2020 Sep;56(3)
- Zhang Q et al., "Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.", Science, 2020 Oct 23;370(6515)
- Severe Covid-19 GWAS Group et al., "Genomewide Association Study of Severe Covid-19 with Respiratory Failure.", N Engl J Med, 2020 Oct 15;383(16):1522-1534
- Muñoa-Hoyos I et al., "Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs.", Clin Epigenetics, 2020 Nov 9;12(1):170
- Lee HK et al., "Regulation of the ACE2 locus in human airways cells.", bioRxiv, 2020 Nov 6;
- Shen LW et al., "Inhibition of Influenza A virus propagation by benzoselenoxanthenes stabilizing TMPRSS2 Gene G-quadruplex and hence down-regulating TMPRSS2 expression.", Sci Rep, 2020 May 6;10(1):7635
- Wang N et al., "Inherited Missense Mutation Occurring in Arginine76 of the SRY Gene Does Not Account for Familial 46, XY Sex Reversal.", J Clin Endocrinol Metab, 2020 May 1;105(5)
- Bullerdiek J "COVID-19 challenging cell biology.", Protoplasma, 2020 May;257(3):619-620
- Landi MT et al., "Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility.", Nat Genet, 2020 May;52(5):494-504
- Diaz-Jimenez D et al., "Glucocorticoids mobilize macrophages by transcriptionally up-regulating the exopeptidase DPP4.", J Biol Chem, 2020 Mar 6;295(10):3213-3227
- Gomes NL et al., "Disorders of Sex Development-Novel Regulators, Impacts on Fertility, and Options for Fertility Preservation.", Int J Mol Sci, 2020 Mar 26;21(7)
- Pang B et al., "Systematic identification of silencers in human cells.", Nat Genet, 2020 Mar;52(3):254-263
- Stopsack KH et al., "TMPRSS2 and COVID-19: Serendipity or Opportunity for Intervention?", Cancer Discov, 2020 Jun;10(6):779-782
- Onabajo OO et al., "Interferons and viruses induce a novel primate-specific isoform dACE2 and not the SARS-CoV-2 receptor ACE2.", bioRxiv, 2020 Jul 20;
- Doni Jayavelu N et al., "Candidate silencer elements for the human and mouse genomes.", Nat Commun, 2020 Feb 26;11(1):1061
- Chaudhri VK et al., "Charting the cis-regulome of activated B cells by coupling structural and functional genomics.", Nat Immunol, 2020 Feb;21(2):210-220
- Martínez de Paz A et al., "Gene regulatory networks STARR-ing B cells.", Nat Immunol, 2020 Feb;21(2):110-112
- Terakawa J et al., "SIX1 cooperates with RUNX1 and SMAD4 in cell fate commitment of Müllerian duct epithelium.", Cell Death Differ, 2020 Dec;27(12):3307-3320
- Ng KW et al., "Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option.", Nat Genet, 2020 Dec;52(12):1294-1302
- Onabajo OO et al., "Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor.", Nat Genet, 2020 Dec;52(12):1283-1293
- Dyagil IS et al., "CHRONIC MYELOID LEUKEMIA COURSE IN PERSONS EXPOSED TO IONIZING RADIATION AS A RESULT OF THE CHORNOBYL ACCIDENT.", Probl Radiac Med Radiobiol, 2020 Dec;25:443-455
- Namburi P et al., "A unique PRDM13-associated variant in a Georgian Jewish family with probable North Carolina macular dystrophy and the possible contribution of a unique CFH variant.", Mol Vis, 2020;26:299-310
- Barker H et al., "Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2.", PLoS One, 2020;15(10):e0240647
- Cai F et al., "[Genetic analysis of one family with congenital limb malformations].", Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2019 Sep 10;36(9):890-892
- Lane WJ et al., "Automated typing of red blood cell and platelet antigens from whole exome sequences.", Transfusion, 2019 Oct;59(10):3253-3263
- Rom A et al., "Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability.", Nat Commun, 2019 Nov 8;10(1):5092
- Zhou S et al., "The mTOR-RUNX1 pathway regulates DC-SIGN expression in renal tubular epithelial cells.", Biochem Biophys Res Commun, 2019 Nov 12;519(3):620-625
- Silva RS et al., "Unique noncoding variants upstream of PRDM13 are associated with a spectrum of developmental retinal dystrophies including progressive bifocal chorioretinal atrophy.", Hum Mutat, 2019 May;40(5):578-587
- Zhou Z et al., "DNA·RNA triple helix formation can function as a cis-acting regulatory mechanism at the human β-globin locus.", Proc Natl Acad Sci U S A, 2019 Mar 26;116(13):6130-6139
- Iwata-Yoshikawa N et al., "Acute Respiratory Infection in Human Dipeptidyl Peptidase 4-Transgenic Mice Infected with Middle East Respiratory Syndrome Coronavirus.", J Virol, 2019 Mar 15;93(6)
- Sang H et al., "Dppa3 is critical for Lin28a-regulated ES cells naïve-primed state conversion.", J Mol Cell Biol, 2019 Jun 1;11(6):474-488
- Emami NC et al., "Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms.", Nat Commun, 2019 Jul 15;10(1):3107
- He D et al., "Long noncoding RNA ABHD11-AS1 promote cells proliferation and invasion of colorectal cancer via regulating the miR-1254-WNT11 pathway.", J Cell Physiol, 2019 Jul;234(7):12070-12079
- Oz-Levi D et al., "Noncoding deletions reveal a gene that is critical for intestinal function.", Nature, 2019 Jul;571(7763):107-111
- Gasperini M et al., "A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens.", Cell, 2019 Jan 10;176(1-2):377-390.e19
- Jiang M et al., "miR-1254 inhibits cell proliferation, migration, and invasion by down-regulating Smurf1 in gastric cancer.", Cell Death Dis, 2019 Jan 10;10(1):32
- Kerschner JL et al., "Screening for Regulatory Variants in 460 kb Encompassing the CFTR Locus in Cystic Fibrosis Patients.", J Mol Diagn, 2019 Jan;21(1):70-80
- Monahan K et al., "LHX2- and LDB1-mediated trans interactions regulate olfactory receptor choice.", Nature, 2019 Jan;565(7740):448-453
- Spitz F "Chromosomes come together to help mice distinguish odours.", Nature, 2019 Jan;565(7740):439-440
- Grinspon RP et al., "Molecular Characterization of XX Maleness.", Int J Mol Sci, 2019 Dec 3;20(23)
- Fulco CP et al., "Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations.", Nat Genet, 2019 Dec;51(12):1664-1669
- Chen Z et al., "Androgen Receptor-Activated Enhancers Simultaneously Regulate Oncogene TMPRSS2 and lncRNA PRCAT38 in Prostate Cancer.", Cells, 2019 Aug 9;8(8)
- Zhao Y et al., "Cathepsin L-mediated resistance of paclitaxel and cisplatin is mediated by distinct regulatory mechanisms.", J Exp Clin Cancer Res, 2019 Aug 1;38(1):333
- Anlıaçık SÖ et al., "Investigation of the relationship between ischemic stroke and endothelial nitric oxide synthase gene polymorphisms [G894T, intron 4 VNTR and T786C].", Turk J Med Sci, 2019 Apr 18;49(2):589-594
- Li B et al., "The Role of HOX Transcription Factors in Cancer Predisposition and Progression.", Cancers (Basel), 2019 Apr 12;11(4)
- Zhao S et al., "Dppa3 in pluripotency maintenance of ES cells and early embryogenesis.", J Cell Biochem, 2019 Apr;120(4):4794-4799
- Huang D et al., "Identification of human silencers by correlating cross-tissue epigenetic profiles and gene expression.", Genome Res, 2019 Apr;29(4):657-667
- Gonen N et al., "The regulation of Sox9 expression in the gonad.", Curr Top Dev Biol, 2019;134:223-252
- Rao C et al., "Mutational Screening of GLI3, SHH, and SHH ZRS in 78 Chinese Children with Nonsyndromic Polydactyly.", Genet Test Mol Biomarkers, 2018 Sep;22(9):577-581
- Suzuki M et al., "Cas9 ribonucleoprotein complex allows direct and rapid analysis of coding and noncoding regions of target genes in Pleurodeles waltl development and regeneration.", Dev Biol, 2018 Nov 15;443(2):127-136
- Huijsdens-van Amsterdam K et al., "Mosaic maternal 10qter deletions are associated with FRA10B expansions and may cause false-positive noninvasive prenatal screening results.", Genet Med, 2018 Nov;20(11):1472-1476
- Potuijt JWP et al., "A point mutation in the pre-ZRS disrupts sonic hedgehog expression in the limb bud and results in triphalangeal thumb-polysyndactyly syndrome.", Genet Med, 2018 Nov;20(11):1405-1413
- Wang JW et al., "Decreased Methylation of IFNAR Gene Promoter from Peripheral Blood Mononuclear Cells Is Associated with Oxidative Stress in Chronic Hepatitis B.", J Interferon Cytokine Res, 2018 Nov;38(11):480-490
- Ogasawara K et al., "The B allele with a 5·8 kb deletion in intron 1 of the ABO gene is the major allele in Japanese individuals with B(m) and A(1) B(m) phenotypes.", Vox Sang, 2018 May;113(4):393-396
- Huang J et al., "Dissecting super-enhancer hierarchy based on chromatin interactions.", Nat Commun, 2018 Mar 5;9(1):943
- Hu X et al., "TAp63 is correlated with chronic inflammation in patients with newly diagnosed type 2 diabetes mellitus.", J Diabetes Complications, 2018 Mar;32(3):335-341
- Gonen N et al., "Sex reversal following deletion of a single distal enhancer of Sox9.", Science, 2018 Jun 29;360(6396):1469-1473
- Dadaev T et al., "Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.", Nat Commun, 2018 Jun 11;9(1):2256
- Smith AJP et al., "Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.", Physiol Genomics, 2018 Jul 1;50(7):510-522
- Steba GS et al., "DC-SIGN Polymorphisms Associate with Risk of Hepatitis C Virus Infection Among Men who Have Sex with Men but not Among Injecting Drug Users.", J Infect Dis, 2018 Jan 17;217(3):353-357
- Wang X et al., "Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice.", Arterioscler Thromb Vasc Biol, 2018 Jan;38(1):76-82
- Croft B et al., "Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9.", Nat Commun, 2018 Dec 14;9(1):5319
- Li Y et al., "Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1.", Nature, 2018 Dec;564(7734):136-140
- Barakat TS et al., "Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells.", Cell Stem Cell, 2018 Aug 2;23(2):276-288.e8
- Ito S et al., "MRGBP promotes AR-mediated transactivation of KLK3 and TMPRSS2 via acetylation of histone H2A.Z in prostate cancer cells.", Biochim Biophys Acta Gene Regul Mech, 2018 Aug 1;
- Mutolo MJ et al., "A transcription factor network represses CFTR gene expression in airway epithelial cells.", Biochem J, 2018 Apr 16;475(7):1323-1334
- Letelier J et al., "A conserved Shh cis-regulatory module highlights a common developmental origin of unpaired and paired fins.", Nat Genet, 2018 Apr;50(4):504-509
- Karamitros T et al., "Impact of Interferon-α Receptor-1 Promoter Polymorphisms on the Transcriptome of the Hepatitis B Virus-Associated Hepatocellular Carcinoma.", Front Immunol, 2018;9:777
- Amano T et al., "Two Types of Etiological Mutation in the Limb-Specific Enhancer of Shh.", G3 (Bethesda), 2017 Sep 7;7(9):2991-2998
- Monahan K et al., "Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons.", Elife, 2017 Sep 21;6
- Li Y et al., "MAP Kinase-Dependent RUNX2 Phosphorylation Is Necessary for Epigenetic Modification of Chromatin During Osteoblast Differentiation.", J Cell Physiol, 2017 Sep;232(9):2427-2435
- Ohnesorg T et al., "A duplication in a patient with 46,XX ovo-testicular disorder of sex development refines the SOX9 testis-specific regulatory region to 24 kb.", Clin Genet, 2017 Sep;92(3):347-349
- Tsai SC et al., "The miR-200b-ZEB1 circuit regulates diverse stemness of human hepatocellular carcinoma.", Mol Carcinog, 2017 Sep;56(9):2035-2047
- Zhang R et al., "Role of the LF-SINE-Derived Distal ISL1 Enhancer in Patients with Classic Bladder Exstrophy.", J Pediatr Genet, 2017 Sep;6(3):169-173
- Wang Z et al., "Significance of the TMPRSS2:ERG gene fusion in prostate cancer.", Mol Med Rep, 2017 Oct;16(4):5450-5458
- Stone L "Prostate cancer: Mastering transcription: TMPRSS2-ERG and the cis-regulatory landscape.", Nat Rev Urol, 2017 Oct;14(10):579
- Kent R et al., "Effects of Fenofibrate on the Expression of Small Heterodimer Partner (SHP) and Cytochrome P450 (CYP) 2D6.", Drug Metab Lett, 2017 Nov 17;11(1):68-72
- Manes G et al., "A novel duplication of PRMD13 causes North Carolina macular dystrophy: overexpression of PRDM13 orthologue in drosophila eye reproduces the human phenotype.", Hum Mol Genet, 2017 Nov 15;26(22):4367-4374
- Mumbach MR et al., "Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements.", Nat Genet, 2017 Nov;49(11):1602-1612
- Vos S et al., "BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers.", Breast Cancer Res, 2017 May 31;19(1):64
- Chuang JY et al., "Upregulation of CYP17A1 by Sp1-mediated DNA demethylation confers temozolomide resistance through DHEA-mediated protection in glioma.", Oncogenesis, 2017 May 22;6(5):e339
- Doyle GA et al., "Reading LINEs within the cocaine addicted brain.", Brain Behav, 2017 May;7(5):e00678
- Chen L et al., "Cyproterone acetate enhances TRAIL-induced androgen-independent prostate cancer cell apoptosis via up-regulation of death receptor 5.", BMC Cancer, 2017 Mar 7;17(1):179
- Bachmann N et al., "Novel deletion in 11p15.5 imprinting center region 1 in a patient with Beckwith-Wiedemann syndrome provides insight into distal enhancer regulation and tumorigenesis.", Pediatr Blood Cancer, 2017 Mar;64(3)
- Dalagiorgou G et al., "Mechanosensor polycystin-1 potentiates differentiation of human osteoblastic cells by upregulating Runx2 expression via induction of JAK2/STAT3 signaling axis.", Cell Mol Life Sci, 2017 Mar;74(5):921-936
- Cheng D et al., "Repression of telomerase gene promoter requires human-specific genomic context and is mediated by multiple HDAC1-containing corepressor complexes.", FASEB J, 2017 Mar;31(3):1165-1178
- Sreenivasan R et al., "Altered SOX9 genital tubercle enhancer region in hypospadias.", J Steroid Biochem Mol Biol, 2017 Jun;170:28-38
- De Santi C et al., "Mesothelin promoter variants are associated with increased soluble mesothelin-related peptide levels in asbestos-exposed individuals.", Occup Environ Med, 2017 Jun;74(6):456-463
- Klann TS et al., "CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome.", Nat Biotechnol, 2017 Jun;35(6):561-568
- Fan R et al., "Preliminary analysis of the association between methylation of the ACE2 promoter and essential hypertension.", Mol Med Rep, 2017 Jun;15(6):3905-3911
- Tang J et al., "Construction of a general albumin promoter reporter system for real-time monitoring of the differentiation status of functional hepatocytes from stem cells in mouse, rat and human.", Biomed Rep, 2017 Jun;6(6):627-632
- Canela A et al., "Genome Organization Drives Chromosome Fragility.", Cell, 2017 Jul 27;170(3):507-521.e18
- Ito R et al., "A ubiquitin-proteasome inhibitor bortezomib suppresses the expression of CYP11B2, a key enzyme of aldosterone synthesis.", Biochem Biophys Res Commun, 2017 Jul 15;489(1):21-28
- Liu SJ et al., "CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells.", Science, 2017 Jan 6;355(6320)
- Khosravi B et al., "Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.", Hum Mol Genet, 2017 Feb 15;26(4):790-800
- Hasenpusch-Theil K et al., "Direct Interactions Between Gli3, Wnt8b, and Fgfs Underlie Patterning of the Dorsal Telencephalon.", Cereb Cortex, 2017 Feb 1;27(2):1137-1148
- Fornari TA et al., "Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.", Exp Biol Med (Maywood), 2017 Feb;242(3):267-274
- Moorthy SD et al., "Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes.", Genome Res, 2017 Feb;27(2):246-258
- Coban N et al., "CYP19A1, MIF and ABCA1 genes are targets of the RORα in monocyte and endothelial cells.", Cell Biol Int, 2017 Feb;41(2):163-176
- Todorova K et al., "Micro-RNA-204 Participates in TMPRSS2/ERG Regulation and Androgen Receptor Reprogramming in Prostate Cancer.", Horm Cancer, 2017 Feb;8(1):28-48
- Ye G et al., "p55PIK regulates alpha-fetoprotein expression through the NF-κB signaling pathway.", Life Sci, 2017 Dec 15;191:104-110
- Iurescia S et al., "Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression.", Mol Neurobiol, 2017 Dec;54(10):8386-8403
- Blauschmidt S et al., "Dipeptidyl peptidase 4 serum activity and concentration are increased in women with polycystic ovary syndrome.", Clin Endocrinol (Oxf), 2017 Dec;87(6):741-747
- Blinka S et al., "Nanog Expression in Embryonic Stem Cells - An Ideal Model System to Dissect Enhancer Function.", Bioessays, 2017 Dec;39(12)
- Cipriani V et al., "Duplication events downstream of IRX1 cause North Carolina macular dystrophy at the MCDR3 locus.", Sci Rep, 2017 Aug 8;7(1):7512
- Lettice LA et al., "The Conserved Sonic Hedgehog Limb Enhancer Consists of Discrete Functional Elements that Regulate Precise Spatial Expression.", Cell Rep, 2017 Aug 8;20(6):1396-1408
- Rojo R et al., "Transcriptional mechanisms that control expression of the macrophage colony-stimulating factor receptor locus.", Clin Sci (Lond), 2017 Aug 15;131(16):2161-2182
- Nagarajan S et al., "BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells.", Nucleic Acids Res, 2017 Apr 7;45(6):3130-3145
- Hofer P et al., "MNS16A tandem repeat minisatellite of human telomerase gene: functional studies in colorectal, lung and prostate cancer.", Oncotarget, 2017 Apr 25;8(17):28021-28027
- Xie S et al., "Multiplexed Engineering and Analysis of Combinatorial Enhancer Activity in Single Cells.", Mol Cell, 2017 Apr 20;66(2):285-299.e5
- Heng J et al., "Integrated analysis of promoter methylation and expression of telomere related genes in breast cancer.", Oncotarget, 2017 Apr 11;8(15):25442-25454
- Pedersen KB et al., "Forkhead Box Transcription Factors of the FOXA Class Are Required for Basal Transcription of Angiotensin-Converting Enzyme 2.", J Endocr Soc, 2017 Apr 1;1(4):370-384
- Lee WS et al., "Epigenetic interplay at the β-globin locus.", Biochim Biophys Acta Gene Regul Mech, 2017 Apr;1860(4):393-404
- Liang Y et al., "Pax5 Re-expression in H460 Cells Treated with the Combination of Demethylating Agent and Histone Deacetylase Inhibitor is Associated with the Enhancement of P53 Binding to Pax5 Promoter Region.", Curr Cancer Drug Targets, 2017;17(2):169-176
- Houwing DJ et al., "The Serotonin Transporter and Early Life Stress: Translational Perspectives.", Front Cell Neurosci, 2017;11:117
- Peplonska B et al., "Rotating night work, lifestyle factors, obesity and promoter methylation in BRCA1 and BRCA2 genes among nurses and midwives.", PLoS One, 2017;12(6):e0178792
- Guo P et al., "Minidumbbell: A New Form of Native DNA Structure.", J Am Chem Soc, 2016 Sep 28;138(38):12534-40
- Blinka S et al., "Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes.", Cell Rep, 2016 Sep 27;17(1):19-28
- Gehrke AR et al., "Cis-regulatory programs in the development and evolution of vertebrate paired appendages.", Semin Cell Dev Biol, 2016 Sep;57:31-39
- Liu L et al., "SIRT1-mediated transcriptional regulation of SOX2 is important for self-renewal of liver cancer stem cells.", Hepatology, 2016 Sep;64(3):814-27
- Wang N et al., "MLL-SEPT5 Fusion Transcript in Two de novo Acute Myeloid Leukemia Patients With t(11;22)(q23;q11).", Ann Lab Med, 2016 Sep;36(5):501-3
- Yao W et al., "Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition.", J Biol Chem, 2016 Oct 7;291(41):21694-21702
- Gao ZJ et al., "Repression of neuronal nitric oxide (nNOS) synthesis by MTA1 is involved in oxidative stress-induced neuronal damage.", Biochem Biophys Res Commun, 2016 Oct 7;479(1):40-7
- Amenya HZ et al., "Dioxin induces Ahr-dependent robust DNA demethylation of the Cyp1a1 promoter via Tdg in the mouse liver.", Sci Rep, 2016 Oct 7;6:34989
- Wei Y et al., "Loss of ZNF32 augments the regeneration of nervous lateral line system through negative regulation of SOX2 transcription.", Oncotarget, 2016 Oct 25;7(43):70420-70436
- Sano R et al., "Epithelial Expression of Human ABO Blood Group Genes Is Dependent upon a Downstream Regulatory Element Functioning through an Epithelial Cell-specific Transcription Factor, Elf5.", J Biol Chem, 2016 Oct 21;291(43):22594-22606
- Kvon EZ et al., "Progressive Loss of Function in a Limb Enhancer during Snake Evolution.", Cell, 2016 Oct 20;167(3):633-642.e11
- Yoh KE et al., "Repression of p63 and induction of EMT by mutant Ras in mammary epithelial cells.", Proc Natl Acad Sci U S A, 2016 Oct 11;113(41):E6107-E6116
- Engreitz JM et al., "Local regulation of gene expression by lncRNA promoters, transcription and splicing.", Nature, 2016 Nov 17;539(7629):452-455
- Fulco CP et al., "Systematic mapping of functional enhancer-promoter connections with CRISPR interference.", Science, 2016 Nov 11;354(6313):769-773
- Mohanty V et al., "Folate Receptor Alpha Upregulates Oct4, Sox2 and Klf4 and Downregulates miR-138 and miR-let-7 in Cranial Neural Crest Cells.", Stem Cells, 2016 Nov;34(11):2721-2732
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