BioProject

Streptococcus suis is an important porcine and zoonotic pathogen for which there is no effective cross-protective vaccine. More...

Streptococcus suis is an important porcine and zoonotic pathogen for which there is no effective cross-protective vaccine. Str. suis is the cause of significant economic losses to the pig production industry worldwide, and there is a need for alternative strategies to prevent colonisation and invasive disease, especially in young pigs. We have explored the microbiota of healthy piglets with the aim to find commensal bacteria that can specifically kill or inhibit the growth of Str. suis. Here we describe the identification and characterization of two short antimicrobial peptides secreted by a commensal Staphylococcus pasteuri strain that effectively inhibit a wide range of Str. suis strains. Less...