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Accession: PRJNA205370 ID: 205370

Homo sapiens (human)

Gene expression study in Neuroblastoma after BET inhibition

See Genome Information for Homo sapiens
We studied transcriptional changes by Illumina HumanHT-12 v4 microarrays in 2 Neuroblastoma cell lines after i-BET-726 treatment Overall design: 2 neuroblastoma cell lines SK-N-SH and CHP-212 were treated with i-BET-726 at 100nM or 1uM concentrations for 16 hrs to study gene expression.
AccessionPRJNA205370; GEO: GSE47386
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsWyce A et al., "BET inhibition silences expression of MYCN and BCL2 and induces cytotoxicity in neuroblastoma tumor models.", PLoS One, 2013;8(8):e72967
SubmissionRegistration date: 26-May-2013
GSK
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets3
GEO Data Details
ParameterValue
Data volume, Spots851814
Data volume, Processed Mbytes27
Data volume, Supplementary Mbytes6

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