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Genome Information for Homo sapiens
We studied transcriptional changes by Illumina HumanHT-12 v4 microarrays in 2 Neuroblastoma cell lines after i-BET-726 treatment
Overall design: 2 neuroblastoma cell lines SK-N-SH and CHP-212 were treated with i-BET-726 at 100nM or 1uM concentrations for 16 hrs to study gene expression.
Accession | PRJNA205370; GEO: GSE47386 |
Data Type | Transcriptome or Gene expression |
Scope | Multiisolate |
Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
Publications | Wyce A et al., "BET inhibition silences expression of MYCN and BCL2 and induces cytotoxicity in neuroblastoma tumor models.", PLoS One, 2013;8(8):e72967 |
Submission | Registration date: 26-May-2013 GSK |
Relevance | Medical |
Project Data:
Resource Name | Number of Links |
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Publications |
PubMed | 1 |
PMC | 1 |
Other datasets |
GEO DataSets | 3 |
GEO Data DetailsParameter | Value |
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Data volume, Spots | 851814 |
Data volume, Processed Mbytes | 27 |
Data volume, Supplementary Mbytes | 6 |