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Accession: PRJNA627345 ID: 627345

Remodeling of white fat during browning involves YBX1 to drive thermogenic commitment (house mouse)

See Genome Information for Mus musculus
Effects of YBX1 activation in PPARγ-indcuded C3H/10T1/2-SAM pre-adipocytes on the transcriptome of cells during early differentation stages Overall design: C3H/10T1/2-SAM pre-adipocytes containing dCas9-VP64 and MS2-P65-HSF1 were transfected with guide RNA taregting PPARγ or a combination of guides taregting PPARγ and YBX1 two days before differentiation start to model gain of funtion in pre-adipocytes. Transcriptome was analysed for day 0, day 2 and day 4 of differentiation.
AccessionPRJNA627345; GEO: GSE149083
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsRabiee A et al., "White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment.", Mol Metab, 2021 Feb;44:101137
SubmissionRegistration date: 22-Apr-2020
Integrative Physiology, NNF Center for Basic Metabolic Research, Copenhagen University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments51
Publications
PubMed1
PMC1
Other datasets
BioSample51
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes3
SRA Data Details
ParameterValue
Data volume, Gbases155
Data volume, Mbytes64388

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