BioProject

This dataset contains whole-genome variant frequencies for 300 individuals from Västerbotten County in Sweden, generated within the a project aimed to find variants giving a predisposition for cancer. More...

This dataset contains whole-genome variant frequencies for 300 individuals from Västerbotten County in Sweden, generated within the a project aimed to find variants giving a predisposition for cancer. The frequency data is intended to be used as a resource for the research community and clinical genetics laboratories.

Please note that the 300 individuals included in ACpop were selected from the Västerbotten Intervention Program, VIP, a biobank with samples from >100,000 individuals in the Västerbotten County. This dataset is based on a cross-section of the population of Västerbotten County, Sweden. The inclusion criteria for the study were that participants should be over 80 years of age and have no diagnosed cancer. Selection of individuals were made according to a statistical design that took 27 health and lifestyle related variables into account. This was done to select as diverse individuals as possible to maximize the genetic diversity. As a consequence, genetic variants contributing to disease risk may or may not occur in the dataset at the general population frequency. There is no explicit or implicit guarantee that the genetic variants in the dataset do not contribute to risk of disease. Less...