This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series
| Accession | PRJNA308610; GEO: GSE76809 |
| Type | Umbrella project |
| Publications (total 3) Less... | - Renaud L et al., "Prominence of IL6, IGF, TLR, and Bioenergetics Pathway Perturbation in Lung Tissues of Scleroderma Patients With Pulmonary Fibrosis.", Front Immunol, 2020;11:383
More...- Renaud L et al., "Prominence of IL6, IGF, TLR, and Bioenergetics Pathway Perturbation in Lung Tissues of Scleroderma Patients With Pulmonary Fibrosis.", Front Immunol, 2020;11:383
- Taroni JN et al., "A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis.", Genome Med, 2017 Mar 23;9(1):27
- Hsu E et al., "Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension.", Arthritis Rheum, 2011 Mar;63(3):783-94
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| Submission | Registration date: 12-Jan-2016
Whitfield Lab, Genetics, Dartmouth Medical School |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 11 |
| PMC | 11 |
| Other datasets |
| GEO DataSets | 11 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 13802518 |
| Data volume, Processed Mbytes | 473 |
| Data volume, Supplementary Mbytes | 2029 |
Multi-tissue functional genomic study of systemic sclerosis encompasses the following 9 sub-projects:
| Project Type | Number of Projects |
| Transcriptome or Gene expression | 9 |
BioProject
accession | Organism | Title |
|---|
| PRJNA308611 | Homo sapiens | Gene expression in limited cutaneous systemic sclerosis skin (Whitfield Lab, Genetics,...) | | PRJNA308612 | Homo sapiens | Gene expression in limited cutaneous SSc skin (Whitfield Lab, Genetics,...) | | PRJNA308613 | Homo sapiens | Association of Interferon- and Transforming Growth Factor -Regulated Genes and Macrophage Activation With Systemic Sclerosis-Related Progressive Lung Fibrosis (Whitfield Lab, Genetics,...) | | PRJNA146381 | Homo sapiens | Stable gene expression of serial skin biopsies defines patient subsets in diffuse cutaneous systemic sclerosis (Whitfield Lab, Genetics,...) | | PRJNA127663 | Homo sapiens | Altered immune phenotype in peripheral blood cells of patients with scleroderma-associated pulmonary hypertension (Pulmonary Sciences and Critical...) | | PRJNA122567 | Homo sapiens | Limited systemic sclerosis patients with PAH show biomarkers of inflammation and vascular injury (Whitfield, Genetics, Dartmouth...) | | PRJNA102919 | Homo sapiens | Gene Expression Profiling of Scleroderma Skin (Whitfield Lab, Genetics,...) | | PRJNA209046 | Homo sapiens | Lung tissues in systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension (Medicine, University of Pittsburgh) | | PRJNA283411 | Homo sapiens | Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signatures (Whitfield Lab, Genetics,...) |
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