The
Biozentrum, University of Basel, Switzerland, in collaboration with
Syngenta,
completed the sequencing of the
Eremothecium gossypii (aka
Ashbya gossypii) strain ATCC 10895 nuclear and mitochondrial genomes in 2001. The nuclear genome is sequenced at approximately 4.2X coverage; regions of low quality are identified. This sequencing project was initiated when a high level of conservation of synteny between
Eremothecium gossypii and
Saccharomyces cerevisiae, which diverged from each other more than 100 million years ago, was discovered. Annotation of the
Eremothecium gossypii genome revealed 4,718 protein-coding genes in the nuclear genome and eight in the mitochondrial genome. Over 90% of the
Eremothecium gossypii genes share both homology and synteny with
Saccharomyces cerevisiae genes. The majority of the
Eremothecium gossypii genes occur in duplicate in
Saccharomyces cerevisiae, which is considered to be evidence that the evolution of
Saccharomyces cerevisiae included either a whole-genome duplication or a fusion of two related species.
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