8QSU: Bi-allelic variants of SPOUT1, a novel RNA methyltransferase, cause chromosome missegregation and a rare neurodevelopmental disease

PDB ID: 8QSUDownload
MMDB ID: 253870
PDB Deposition Date: 2023/10/11
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.38  Å
Source Organism:
Similar Structures:
Biological Unit for 8QSU: dimeric; determined by author and by software (PISA)
Molecular Components in 8QSU
Label Count Molecule
Proteins (2 molecules)
2
Putative Methyltransferase C9orf114
(Gene symbol: SPOUT1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303