7XTQ: Cryo-EM structure of the R399-bound GPBAR-Gs complex

PDB ID: 7XTQDownload
MMDB ID: 217495
PDB Deposition Date: 2022/5/17
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7XTQ: pentameric; determined by author
Molecular Components in 7XTQ
Label Count Molecule
Proteins (5 molecules)
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nanobody-35
Molecule annotation
1
G-protein Coupled Bile Acid Receptor 1
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
[2-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone[2-(2,5-Dichloro-phenoxy)-pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)-methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303