7W9K: Cryo-EM structure of human Nav1.7-beta1-beta2 complex at 2.2 angstrom resolution

PDB ID: 7W9KDownload
MMDB ID: 216083
PDB Deposition Date: 2021/12/9
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 7W9K: trimeric; determined by author
Molecular Components in 7W9K
Label Count Molecule
Proteins (3 molecules)
1
Sodium Channel Protein Type 9 Subunit Alpha
(Gene symbol: SCN9A)
Molecule annotation
1
Sodium Channel Subunit Beta-1
(Gene symbol: SCN1B)
Molecule annotation
1
Sodium Channel Subunit Beta-2
(Gene symbol: SCN2B)
Molecule annotation
Chemicals and Non-standard biopolymers (43 molecules)
1
11
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
3
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serineO-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine
3
6
CHOLESTEROL HEMISUCCINATECHOLESTEROL HEMISUCCINATE
4
1
(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en(3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en
5
1
SODIUM IONSODIUM ION
6
15
1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE
7
1
(2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate(2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
8
5
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303