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7NWL:
Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp
PDB ID:
7NWL
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MMDB ID:
202767
PDB Deposition Date:
2021/3/17
Updated in MMDB:
2021/10
Experimental Method:
electron microscopy
Resolution:
3.1 Å
Source Organism:
Mus musculus
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Taxonomy
Molecule
Mus musculus
D, E
Homo sapiens
A, B, C
Similar Structures:
VAST+
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Biological Unit for 7NWL: pentameric; determined by author and by software (PISA)
Molecular Components in 7NWL
Label
Count
Molecule
Proteins (5 molecules)
A
1
Integrin Alpha-5
B
1
Integrin Beta-1
C
1
Isoform 1 of Fibronectin
D
1
Ts2/16 Vh(s112c)-sarah Chimera
E
1
Ts2/16 Vl-sarah(s37c) Chimera
Chemicals and Non-standard biopolymers (40 molecules)
1
21
2-acetamido-2-deoxy-beta-D-glucopyranose
2
7
beta-D-mannopyranose
3
5
alpha-D-mannopyranose
4
7
MANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303