6UYA: Crystal structure of Compound 19 bound to IRAK4

PDB ID: 6UYADownload
MMDB ID: 181594
PDB Deposition Date: 2019/11/12
Updated in MMDB: 2019/11
Experimental Method:
x-ray diffraction
Resolution: 1.74  Å
Source Organism:
Similar Structures:
Biological Unit for 6UYA: tetrameric; determined by author and by software (PISA)
Molecular Components in 6UYA
Label Count Molecule
Proteins (4 molecules)
4
Interleukin-1 Receptor-associated Kinase 4
(Gene symbol: IRAK4)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
N-{2-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-6-(morpholin-4-yl)-1-oxo-2,3-dihydro-1H-isoindol-5-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamideN-{2-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-6-(morpholin-4-yl)-1-oxo-2,3-dihydro-1H-isoindol-5-yl}pyrazolo[1,5-a]pyrimidine-3-carboxamide
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303