6G90: Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2)

PDB ID: 6G90Download
MMDB ID: 165973
PDB Deposition Date: 2018/4/10
Updated in MMDB: 2022/11
Experimental Method:
electron microscopy
Resolution: 4  Å
Source Organism:
Similar Structures:
Biological Unit for 6G90: 38-meric; determined by author
Molecular Components in 6G90
Label Count Molecule
Proteins (35 molecules)
1
U1 Small Nuclear Ribonucleoprotein A,u1 Small Nuclear Ribonucleoprotein A,u1 Small Nuclear Ribonucleoprotein A,u1 Small Nuclear Ribonucleoprotein A,u1 Small Nuclear Ribonucleoprotein a
(Gene symbol: MUD1)
Molecule annotation
1
U1 Small Nuclear Ribonucleoprotein 70 KDA Homolog,u1 Small Nuclear Ribonucleoprotein 70 KDA Homolog,u1 Small Nuclear Ribonucleoprotein 70 KDA Homolog
(Gene symbol: SNP1)
Molecule annotation
1
U1 Small Nuclear Ribonucleoprotein C
(Gene symbol: YHC1)
Molecule annotation
1
Pre-mrna-processing Factor 39
(Gene symbol: PRP39)
Molecule annotation
1
U1 Small Nuclear Ribonucleoprotein Component Prp42
(Gene symbol: PRP42)
Molecule annotation
1
Protein Nam8
(Gene symbol: NAM8)
Molecule annotation
1
56 KDA U1 Small Nuclear Ribonucleoprotein Component
(Gene symbol: SNU56)
Molecule annotation
1
Protein Luc7,protein Luc7,protein Luc7
(Gene symbol: LUC7)
Molecule annotation
1
U1 Small Nuclear Ribonucleoprotein Component Snu71
(Gene symbol: SNU71)
Molecule annotation
1
U2 Snrnp Component Hsh155
(Gene symbol: HSH155)
Molecule annotation
1
Pre-mrna-splicing Factor Rse1
(Gene symbol: RSE1)
Molecule annotation
1
Cold Sensitive U2 Snrna Suppressor 1
(Gene symbol: CUS1)
Molecule annotation
1
Protein Hsh49
(Gene symbol: HSH49)
Molecule annotation
1
Pre-mrna-splicing Factor Rds3
(Gene symbol: RDS3)
Molecule annotation
1
Pre-mrna-splicing Factor Prp9
(Gene symbol: PRP9)
Molecule annotation
1
Pre-mrna-splicing Factor Prp11,pre-mrna-splicing Factor Prp11,pre-mrna-splicing Factor Prp11
(Gene symbol: PRP11)
Molecule annotation
1
Pre-mrna-splicing Factor Prp21
(Gene symbol: PRP21)
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein A'
(Gene symbol: LEA1)
Molecule annotation
1
Unknown
Molecule annotation
1
U2 Small Nuclear Ribonucleoprotein B''
(Gene symbol: MSL1)
Molecule annotation
1
Rds3 Complex Subunit 10
(Gene symbol: YSF3)
Molecule annotation
2
Small Nuclear Ribonucleoprotein-associated Protein B
(Gene symbol: SMB1)
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D3
(Gene symbol: SMD3)
Molecule annotation
2
Small Nuclear Ribonucleoprotein E
(Gene symbol: SME1)
Molecule annotation
2
Small Nuclear Ribonucleoprotein F
(Gene symbol: SMX3)
Molecule annotation
2
Small Nuclear Ribonucleoprotein G
(Gene symbol: SMX2)
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D1
(Gene symbol: SMD1)
Molecule annotation
2
Small Nuclear Ribonucleoprotein SM D2
(Gene symbol: SMD2)
Molecule annotation
Nucleotides(3 molecules)
1
U1 Snrna,u1 Snrna,u1 Snrna,u1 Snrna,u1 Snrna
Molecule annotation
1
U2 Snrna
Molecule annotation
1
Yeast Ubc4 Pre-mrna (Mutant)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
9
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303