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5W2E:
HCV NS5B RNA-dependent RNA polymerase in complex with non-nucleoside inhibitor MK-8876
PDB ID:
5W2E
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MMDB ID:
153746
PDB Deposition Date:
2017/6/6
Updated in MMDB:
2023/10
Experimental Method:
x-ray diffraction
Resolution:
2.8 Å
Source Organism:
Hepatitis C virus (isolate BK)
Similar Structures:
VAST+
Download sequence data
Biological Unit for 5W2E: monomeric; determined by author
Molecular Components in 5W2E
Label
Count
Molecule
Protein (1 molecule)
A
1
Genome Polyprotein
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-(4-fluorophenyl)-5-(11-fluoro-6H-pyrido[2',3':5,6][1,3]oxazino[3,4-a]indol-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303