5VCV: CRYSTAL STRUCTURE OF HUMAN MYT1 KINASE DOMAIN IN COMPLEX WITH Dasatinib

PDB ID: 5VCVDownload
MMDB ID: 153924
PDB Deposition Date: 2017/4/1
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 1.92  Å
Source Organism:
Similar Structures:
Biological Unit for 5VCV: monomeric; determined by author and by software (PISA)
Molecular Components in 5VCV
Label Count Molecule
Protein (1 molecule)
1
Membrane-associated Tyrosine- and Threonine-specific Cdc2-inhibitory Kinase
(Gene symbol: PKMYT1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDEN-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303