5UGX: Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 2 Harboring a E565A/D650V double Gain-of-Function Mutation

PDB ID: 5UGXDownload
MMDB ID: 147608
PDB Deposition Date: 2017/1/10
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.349  Å
Source Organism:
Similar Structures:
Biological Unit for 5UGX: monomeric; determined by author and by software (PISA)
Molecular Components in 5UGX
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 2
(Gene symbol: FGFR2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
SULFATE IONSULFATE ION
2
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
3
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303