5SUN: IDH1 R132H in complex with IDH146

PDB ID: 5SUNDownload
MMDB ID: 147167
PDB Deposition Date: 2016/8/3
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.477  Å
Source Organism:
Similar Structures:
Biological Unit for 5SUN: dimeric; determined by author and by software (PISA)
Molecular Components in 5SUN
Label Count Molecule
Proteins (2 molecules)
2
Isocitrate Dehydrogenase [nadp] Cytoplasmic
(Gene symbol: IDH1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
3-benzyl-N-[3-(dimethylsulfamoyl)phenyl]-4-oxo-3,4-dihydrophthalazine-1-carboxamide3-benzyl-N-[3-(dimethylsulfamoyl)phenyl]-4-oxo-3,4-dihydrophthalazine-1-carboxamide
3
4
SULFATE IONSULFATE ION
4
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303