5NQR: Potent inhibitors of NUDT5 silence hormone signaling in breast cancer

PDB ID: 5NQRDownload
MMDB ID: 158620
PDB Deposition Date: 2017/4/21
Updated in MMDB: 2018/02
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5NQR: dimeric; determined by author and by software (PISA)
Molecular Components in 5NQR
Label Count Molecule
Proteins (2 molecules)
2
Adp-sugar Pyrophosphatase
(Gene symbol: NUDT5)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
3
8-(dimethylamino)-1,3-dimethyl-7-[[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl]purine-2,6-dione8-(dimethylamino)-1,3-dimethyl-7-[[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]methyl]purine-2,6-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303