5ACB: Crystal Structure Of The Human Cdk12-cyclink Complex

PDB ID: 5ACBDownload
MMDB ID: 140029
PDB Deposition Date: 2015/8/14
Updated in MMDB: 2016/10
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 5ACB: dimeric; determined by software (PISA)
Molecular Components in 5ACB
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-k
Molecule annotation
1
Cyclin-dependent Kinase 12
(Gene symbol: CDK12)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[4-[(3r)-3-[[5-Chloranyl-4-(1h-Indol-3-Yl)pyrimidin-2-Yl]amino]piperidin-1-Yl]carbonylphenyl]-4-(Dimethylamino)butanamideN-[4-[(3r)-3-[[5-Chloranyl-4-(1h-Indol-3-Yl)pyrimidin-2-Yl]amino]piperidin-1-Yl]carbonylphenyl]-4-(Dimethylamino)butanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303