National Center for
Biotechnology Information

4WFA: The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with linezolid

PDB ID:

MMDB ID:

133483

PDB Deposition Date:

2014/9/14

Updated in MMDB:

2024/12

Experimental Method:

x-ray diffraction

Resolution:

3.392 Å

Source Organism:

Staphylococcus aureus subsp. aureus USA300▼

Taxonomy	Molecule
Staphylococcus aureus subsp. aureus USA300	S
Staphylococcus aureus subsp. aureus NCTC 8325	X, Y, A, B, C, D, E, G, H, I, J, K, L, M, N, O, P, Q, R, T, U, V, W, Z, 2, 3, 4

Similar Structures:

Biological Unit for 4WFA: 28-meric; determined by author and by software (PISA)

Molecular Components in 4WFA
Label	Count	Molecule
Proteins (26 molecules)
A	1	50S Ribosomal Protein L2
B	1	50S Ribosomal Protein L3
C	1	50S Ribosomal Protein L4
D	1	50S Ribosomal Protein L5
E	1	50S Ribosomal Protein L6
G	1	50S Ribosomal Protein L13
H	1	50S Ribosomal Protein L14
I	1	50S Ribosomal Protein L15
J	1	50S Ribosomal Protein L16
K	1	50S Ribosomal Protein L17
L	1	50S Ribosomal Protein L18
M	1	50S Ribosomal Protein L19
N	1	50S Ribosomal Protein L20
O	1	50S Ribosomal Protein L21
P	1	50S Ribosomal Protein L22
Q	1	50S Ribosomal Protein L23
R	1	50S Ribosomal Protein L24
S	1	50S Ribosomal Protein L25
T	1	50S Ribosomal Protein L27
U	1	50S Ribosomal Protein L28
V	1	50S Ribosomal Protein L29
W	1	50S Ribosomal Protein L30
Z	1	50S Ribosomal Protein L32
2	1	50S Ribosomal Protein L34
3	1	50S Ribosomal Protein L35
4	1	50S Ribosomal Protein L36
Nucleotides(2 molecules)
X	1	23S rRNA
Y	1	5S rRNA
Chemicals and Non-standard biopolymers (470 molecules)
1	1	N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
2	9	(4S)-2-METHYL-2,4-PENTANEDIOL
3	246	MAGNESIUM ION
4	195	MANGANESE (II) ION
5	1	SODIUM ION
6	4	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
7	9	SPERMIDINE
8	5	ETHANOL

* Click molecule labels to explore molecular sequence information.

Citing MMDB