4UX8: RET recognition of GDNF-GFRalpha1 ligand by a composite binding site promotes membrane-proximal self-association

PDB ID: 4UX8Download
MMDB ID: 154013
PDB Deposition Date: 2014/8/19
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 24  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 4UX8: hexameric; determined by software (PISA)
Molecular Components in 4UX8
Label Count Molecule
Proteins (6 molecules)
2
Proto-oncogene Tyrosine-protein Kinase Receptor RET
Molecule annotation
2
Gdnf Family Receptor Alpha-1
Molecule annotation
2
Glial Cell Line-derived Neurotrophic Factor
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
6
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303