4Q0N: Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand

PDB ID: 4Q0NDownload
MMDB ID: 119640
PDB Deposition Date: 2014/4/2
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.78  Å
Source Organism:
Similar Structures:
Biological Unit for 4Q0N: monomeric; determined by author and by software (PISA)
Molecular Components in 4Q0N
Label Count Molecule
Protein (1 molecule)
1
Protein Polybromo-1
(Gene symbol: PBRM1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
(2E)-1-(2-hydroxyphenyl)-3-(2,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)prop-2-en-1-one(2E)-1-(2-hydroxyphenyl)-3-(2,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridin-6-yl)prop-2-en-1-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303