4MYQ: Selective Inhibition of the Catalytic Domain Of Human Phosphodiesterase 4B With A-33

PDB ID: 4MYQDownload
MMDB ID: 116406
PDB Deposition Date: 2013/9/27
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 4MYQ: monomeric; determined by author and by software (PISA)
Molecular Components in 4MYQ
Label Count Molecule
Protein (1 molecule)
1
Camp-specific 3',5'-cyclic Phosphodiesterase 4B
(Gene symbol: PDE4B)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
(4-{[2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpyrimidin-4-yl]amino}phenyl)acetic acid(4-{[2-(5-chlorothiophen-2-yl)-5-ethyl-6-methylpyrimidin-4-yl]amino}phenyl)acetic acid
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
ZINC IONZINC ION
4
1
SODIUM IONSODIUM ION
5
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303