4AW0: Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the PIF-Pocket

PDB ID: 4AW0Download
MMDB ID: 103497
PDB Deposition Date: 2012/5/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.43  Å
Source Organism:
Similar Structures:
Biological Unit for 4AW0: monomeric; determined by software (PISA)
Molecular Components in 4AW0
Label Count Molecule
Protein (1 molecule)
1
3-phosphoinositide-dependent Protein Kinase 1
(Gene symbol: PDPK1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
2
1
[(1R)-3-(4-chlorophenyl)-3-oxo-1-phenylpropyl]propanedioic acid[(1R)-3-(4-chlorophenyl)-3-oxo-1-phenylpropyl]propanedioic acid
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
2
MAGNESIUM IONMAGNESIUM ION
5
1
DITHIANE DIOLDITHIANE DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303