4A7I: Factor Xa in complex with a potent 2-amino-ethane sulfonamide inhibitor

PDB ID: 4A7IDownload
MMDB ID: 96965
PDB Deposition Date: 2011/11/14
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 4A7I: dimeric; determined by author and by software (PISA)
Molecular Components in 4A7I
Label Count Molecule
Proteins (2 molecules)
1
Factor X Light Chain
(Gene symbol: F10)
Molecule annotation
1
Activated Factor XA Heavy Chain XA
(Gene symbol: F10)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
CALCIUM IONCALCIUM ION
2
1
5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID [2-(1--ISOPROPYL-PIPERIDIN-4-YLSULFAMOYL)-ETHYL]-AMIDE5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID [2-(1--ISOPROPYL-PIPERIDIN-4-YLSULFAMOYL)-ETHYL]-AMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303