3ZH8: A novel small molecule aPKC inhibitor

PDB ID: 3ZH8Download
MMDB ID: 107869
PDB Deposition Date: 2012/12/20
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.739  Å
Source Organism:
Similar Structures:
Biological Unit for 3ZH8: monomeric; determined by author and by software (PISA)
Molecular Components in 3ZH8
Label Count Molecule
Protein (1 molecule)
1
Protein Kinase C Iota Type
(Gene symbol: PRKCI)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
4
IODIDE IONIODIDE ION
2
1
CHLORIDE IONCHLORIDE ION
3
1
(2S)-3-phenyl-N~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine(2S)-3-phenyl-N~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine
4
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303