3V7T: Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold

PDB ID: 3V7TDownload
MMDB ID: 97999
PDB Deposition Date: 2011/12/22
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.09  Å
Source Organism:
Similar Structures:
Biological Unit for 3V7T: tetrameric; determined by author and by software (PISA)
Molecular Components in 3V7T
Label Count Molecule
Proteins (4 molecules)
4
Tpsb2 Protein
(Gene symbol: TPSB2)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
{(3-exo)-3-[5-(aminomethyl)-2-fluorophenyl]-8-azabicyclo[3.2.1]oct-8-yl}(4-bromo-3-methyl-5-propoxythiophen-2-yl)methanone{(3-exo)-3-[5-(aminomethyl)-2-fluorophenyl]-8-azabicyclo[3.2.1]oct-8-yl}(4-bromo-3-methyl-5-propoxythiophen-2-yl)methanone
2
2
CARBONATE IONCARBONATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303