3U1Y: Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

PDB ID: 3U1YDownload
MMDB ID: 96235
PDB Deposition Date: 2011/9/30
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3U1Y: monomeric; determined by author
Molecular Components in 3U1Y
Label Count Molecule
Protein (1 molecule)
1
Udp-3-o-[3-hydroxymyristoyl] N-acetylglucosamine Deacetylase
(Gene symbol: lpxC)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
(2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{4'-[3-(morpholin-4-yl)propoxy]biphenyl-4-yl}butanamide(2R)-N-hydroxy-2-methyl-2-(methylsulfonyl)-4-{4'-[3-(morpholin-4-yl)propoxy]biphenyl-4-yl}butanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303