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3RWQ:
Discovery of a Novel, Potent and Selective Inhibitor of 3-Phosphoinositide Dependent Kinase (PDK1)
PDB ID:
3RWQ
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MMDB ID:
95050
PDB Deposition Date:
2011/5/9
Updated in MMDB:
2011/12
Experimental Method:
x-ray diffraction
Resolution:
2.55 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3RWQ: monomeric; determined by author
Molecular Components in 3RWQ
Label
Count
Molecule
Protein (1 molecule)
A
1
3-phosphoinositide-dependent Protein Kinase 1
(Gene symbol:
PDPK1
)
Chemicals and Non-standard biopolymers (11 molecules)
1
1
[4-amino-7-(propan-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl](6-{[2-(pyridin-3-yl)ethyl]amino}pyrazin-2-yl)methanone
2
3
GLYCEROL
3
7
SULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303