3QKD: Crystal structure of Bcl-xL in complex with a Quinazoline sulfonamide inhibitor

PDB ID: 3QKDDownload
MMDB ID: 89730
PDB Deposition Date: 2011/1/31
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.02  Å
Source Organism:
Similar Structures:
Biological Unit for 3QKD: monomeric; determined by author and by software (PISA)
Molecular Components in 3QKD
Label Count Molecule
Protein (1 molecule)
1
Bcl-2-like Protein 1
(Gene symbol: BCL2L1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(R)-N-(7-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)quinazolin-4-yl)-4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrobenzenesulfonamide(R)-N-(7-(4-((4'-chlorobiphenyl-2-yl)methyl)piperazin-1-yl)quinazolin-4-yl)-4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrobenzenesulfonamide
2
1
CHLORIDE IONCHLORIDE ION
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303