3NCZ: X-Ray Co-structure of Rho-Associated Protein Kinase (ROCK1) with a potent 2H-isoquinolin-1-one inhibitor

PDB ID: 3NCZDownload
MMDB ID: 87172
PDB Deposition Date: 2010/6/6
Updated in MMDB: 2010/12
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 3NCZ: dimeric; determined by author and by software (PISA)
Molecular Components in 3NCZ
Label Count Molecule
Proteins (2 molecules)
2
Rho-associated Protein Kinase 1
(Gene symbol: ROCK1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
cis-4-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamidecis-4-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6-yl)cyclohexanecarboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303