3N7O: X-ray structure of human chymase in complex with small molecule inhibitor

PDB ID: 3N7ODownload
MMDB ID: 83532
PDB Deposition Date: 2010/5/27
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3N7O: monomeric; determined by author and by software (PISA)
Molecular Components in 3N7O
Label Count Molecule
Protein (1 molecule)
1
Chymase
(Gene symbol: CMA1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
4
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
(S)-[(1S)-1-(5-chloro-1-benzothiophen-3-yl)-2-{[(E)-2-(3,4-difluorophenyl)ethenyl]amino}-2-oxoethyl]methylphosphinic acid(S)-[(1S)-1-(5-chloro-1-benzothiophen-3-yl)-2-{[(E)-2-(3,4-difluorophenyl)ethenyl]amino}-2-oxoethyl]methylphosphinic acid
3
2
UNKNOWN LIGANDUNKNOWN LIGAND
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303