3MEC: HIV-1 Reverse Transcriptase in Complex with TMC125

PDB ID: 3MECDownload
MMDB ID: 82081
PDB Deposition Date: 2010/3/31
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 3MEC: dimeric; determined by author and by software (PISA)
Molecular Components in 3MEC
Label Count Molecule
Proteins (2 molecules)
1
P66 Reverse Transcriptase
Molecule annotation
1
P51 Reverse Transcriptase
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE
2
5
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303