3E0P: The X-ray structure of Human Prostasin in complex with a covalent benzoxazole inhibitor

PDB ID: 3E0PDownload
MMDB ID: 66647
PDB Deposition Date: 2008/7/31
Updated in MMDB: 2008/11
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3E0P: monomeric; determined by author and by software (PISA)
Molecular Components in 3E0P
Label Count Molecule
Protein (1 molecule)
1
Prostasin
(Gene symbol: PRSS8)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
benzyl [(1R)-1-({(2S,4R)-2-({(1S)-5-amino-1-[(S)-1,3-benzoxazol-2-yl(hydroxy)methyl]pentyl}carbamoyl)-4-[(4-methylbenzyl)oxy]pyrrolidin-1-yl}carbonyl)-3-phenylpropyl]carbamatebenzyl [(1R)-1-({(2S,4R)-2-({(1S)-5-amino-1-[(S)-1,3-benzoxazol-2-yl(hydroxy)methyl]pentyl}carbamoyl)-4-[(4-methylbenzyl)oxy]pyrrolidin-1-yl}carbonyl)-3-phenylpropyl]carbamate
2
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303