2XK8: Structure of Nek2 bound to aminopyrazine compound 15

PDB ID: 2XK8Download
MMDB ID: 85710
PDB Deposition Date: 2010/7/7
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.001  Å
Source Organism:
Similar Structures:
Biological Unit for 2XK8: monomeric; determined by software (PISA)
Molecular Components in 2XK8
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Nek2
(Gene symbol: NEK2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-methoxybenzoic acid4-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-2-methoxybenzoic acid
2
4
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303