2WC0: crystal structure of human insulin degrading enzyme in complex with iodinated insulin

PDB ID: 2WC0Download
MMDB ID: 70333
PDB Deposition Date: 2009/3/6
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2WC0: trimeric; determined by author and by software (PISA)
Molecular Components in 2WC0
Label Count Molecule
Proteins (3 molecules)
1
Insulin-degrading Enzyme
(Gene symbol: IDE)
Molecule annotation
1
Insulin a Chain
(Gene symbol: INS)
Molecule annotation
1
Insulin B Chain
(Gene symbol: INS)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ZINC IONZINC ION
2
4
1,4-DIETHYLENE DIOXIDE1,4-DIETHYLENE DIOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303