2R4B: ErbB4 kinase domain complexed with a thienopyrimidine inhibitor

PDB ID: 2R4BDownload
MMDB ID: 63095
PDB Deposition Date: 2007/8/31
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 2R4B: monomeric; determined by author and by software (PISA)
Molecular Components in 2R4B
Label Count Molecule
Protein (1 molecule)
1
Receptor Tyrosine-protein Kinase Erbb-4
(Gene symbol: ERBB4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amineN-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303