2O8H: Crystal structure of the catalytic domain of rat phosphodiesterase 10A

PDB ID: 2O8HDownload
MMDB ID: 44129
PDB Deposition Date: 2006/12/12
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2O8H: monomeric; determined by author
Molecular Components in 2O8H
Label Count Molecule
Protein (1 molecule)
1
Phosphodiesterase-10a
(Gene symbol: Pde10a)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
6,7-DIMETHOXY-4-{8-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]-3,4-DIHYDROISOQUINOLIN-2(1H)-YL}QUINAZOLINE6,7-DIMETHOXY-4-{8-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]-3,4-DIHYDROISOQUINOLIN-2(1H)-YL}QUINAZOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303