2NVU: Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex

PDB ID: 2NVUDownload
MMDB ID: 44074
PDB Deposition Date: 2006/11/13
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2NVU: pentameric; determined by author
Molecular Components in 2NVU
Label Count Molecule
Proteins (5 molecules)
1
Nedd8-activating Enzyme E1 Regulatory Subunit
(Gene symbol: NAE1)
Molecule annotation
1
Maltose Binding Protein/nedd8-activating Enzyme E1 Catalytic Subunit Chimera
(Gene symbol: UBA3)
Molecule annotation
1
Nedd8-conjugating Enzyme Ubc12
(Gene symbol: UBE2M)
Molecule annotation
2
Nedd8
(Gene symbol: NEDD8)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
ZINC IONZINC ION
3
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303