2IW5: Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase

PDB ID: 2IW5Download
MMDB ID: 41237
PDB Deposition Date: 2006/6/26
Updated in MMDB: 2007/10
Experimental Method:
x-ray diffraction
Resolution: 2.57  Å
Source Organism:
Similar Structures:
Biological Unit for 2IW5: dimeric; determined by author and by software (PQS)
Molecular Components in 2IW5
Label Count Molecule
Proteins (2 molecules)
1
Lysine-specific Histone Demethylase 1
(Gene symbol: KDM1A)
Molecule annotation
1
Rest Corepressor 1
(Gene symbol: RCOR1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
2
3
CHLORIDE IONCHLORIDE ION
3
2
GLYCEROLGLYCEROL
4
1
AMMONIUM IONAMMONIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303